Steven V. Joyal
See book keywords and concepts |
 Prevention of relapse following cognitive therapy vs medications in moderate to severe depression. Arch Gen Psychiatry 2005 Apr; 62(4):4l7-22.
Innes KE et al. Risk indices associated with the insulin resistance syndrome, cardiovascular disease, and possible protection with yoga: A systematic review. / Am Board Fam Pract 2005 Nov-Dec; 18(6):491-519.
Knowler WC et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002 Feb 7; 346(6):393-403.
Ludman E et al. Panic episodes among patients with diabetes. |
Mark Sircus
See book keywords and concepts |
 This can then cause a severe depression or diabetes or hypoglycemia or many other problems as both estrogen and magnesium levels drop through the years."
The use of contraceptives, and estrogen replacement therapies cause magnesium deficiencies.12
When you realize that more than three hundred types of tissues throughout the body have receptors for estrogen ?which is to say that they're affected in some way by the hormone ?it's not surprising that its decrease would cause physical changes. |
Stephen T. Sinatra, M.D.
See book keywords and concepts |
 CAD causes a severe depression in the cardiac energy pool. Patients with CAD are often weak and have bouts of ischemia commonly known as angina—which can be experienced as a wide variety of physical discomforts from classic chest pain or pressure to referred symptoms like throat tightness, arm heaviness or discomfort, shortness of breath, indigestion, toothache, and so on—associated with the heart's inability to supply enough energy. |
| This plaque formation restricts blood flow to the heart muscle itself and deprives the heart cells of oxygen, forcing them to use their energy supply faster than it can be restored, and causing severe depression of the energy pool in affected tissue. Also called ischemic heart disease.
Delayed onset muscle soreness (DOMS). Muscle soreness and stiffness that usually remain for several days following strenuous exercise in healthy, normal individuals.
De novo. A Latin term meaning "new." In biochemical terms, de novo synthesis refers to the cell's ability to form new compounds. |
Gary Null and Amy McDonald
See book keywords and concepts |
 Results of this meta-analysis involving 2 3 randomized studies, 15 of which were placebo-controlled, found that hypericum extracts proved significantly effective in the treatment of patients suffering from moderate to mildly severe depression.
Cimicifuga for Depression. Frances D. Medical Herbalism, 1995 Spring/Summer, 7(l-2):l-2.
This article reports on the successful use of black cohosh in tincture form as a treatment for depression in three different case studies.
Treatment of Depressive Symptoms with a High Concentration Hypericum Preparation. |
Steven V. Joyal
See book keywords and concepts |
| Cognitive therapy vs medications in the treatment of moderate to severe depression. Arch Gen Psychiatry 2005 Apr; 62(4):409-l6.
Eren I et al. The effect of depression on quality of life of patients with type II diabetes mellitus. Depress Anxiety 2007 Feb 20.
Feldman G. Cognitive and behavioral therapies for depression: Overview, new directions, and practical recommendations for dissemination. Psychiatr Clin North Am 2007 Mar; 30(l):39-50.
Georgiades A et al. Study presented at the American Psychosomatic Society annual meeting, Budapest, Hungary, March 2007.
Granath J et al. |
Gary Null and Amy McDonald
See book keywords and concepts |
| Rogers, "phosphatidyl choline in its pure form has made a dramatic difference for many people with severe depression. It should, because the cell membranes are where the "happy hormones" or the neurotransmitters have to hook into the cell. In order for them to insert into these cell membranes, the receptors have to be healthy. Healthy receptors in the membrane are made out of the constituents that make up cell membrane. Phosphatidyl choline is one of those. People just don't get enough of it any more because they don't eat beans, which are rich in phosphatidyl choline. |
| In many cases, weight loss is a symptom of severe depression. In other cases, there is substantial weight gain.
As Dr. Goldwag notes, significant weight loss is likely to bring about "marked deprivation of the essential nutrients, including the amino acids needed to manufacture the proper proteins, as well as a deficiency in many vitamins and minerals. That in itself can then aggravate the depression."
There are many straightforward solutions to at least some of the challenges associated with depression. Dr. Goldwag suggests preparing food in advance. |
J. Douglas Bremner
See book keywords and concepts |
 The Danish Study Group found that the older tricyclic medication clomipramine worked better for severe depression than paroxetine, although it had more side effects. A review from fifteen years ago showed that fluoxetine was only modestly more effective than placebo, with more than 80% of the improvement accounted for by a placebo effect.2 A more recent metaanalysis from data submitted to the FDA showed that 80% of the improvement with antidepressants comes from the placebo response. |
| V ft ft E x a i: ] 'j e
A number of studies dating from the mid-1990s to more recently show that cardiovascular and resistance or weight training combat mild to severe depression. It turns out that exercise results in a surge of serotonin, the neurotransmitter that makes us feel good right after working out, as well as in a long-term mood shift once we've started exercising regularly, effects that may be related in part to an increased growth in brain cells. |
| Other Systemic Treatments for Acne
A few other systemic treatments for acne have unpleasant side effects but so far have not been linked to severe depression or suicide, making them safer alternatives for teens with acne.
DAPSONE
Dapsone is an anti-inflammatory medication used in the treatment of leprosy whose mechanism of action is poorly understood. It can be used as a second line of treatment for acne. Side effects include upset stomach, vomiting, sore throat, fever, and sun sensitivity. It should not be taken by pregnant or breastfeeding women or by patients with anemia or liver disease. |
| John's-wort: There was only about a 15% increase in efficacy over placebo for severe depression. Another meta-analysis of St.-John's-wort for both major and minor depression was consistent with greater efficacy: about a 60% increase over placebo.
Overall, St.-John's-wort probably is effective for the treatment of minor depression, and, based on its biological activity, there is a plausible mechanism that explains why. The surprising thing is that the limited research evidence suggests that it is just as effective as the SSRIs for mild depression. St. |
Tom Bohager
See book keywords and concepts |
 This condition is called premenstrual dysphoric disorder and is characterized by severe depression, irritability, and tension.
Hormonal changes that occur throughout the menstrual cycle clearly influence PMS, but there is no established, concrete cause for the symptoms. PMS may cause mood swings, irritability, tension, depression, anxiety, and fatigue. Physical symptoms may include breast tenderness, fluid retention, headaches, backaches, cramping, bloating, and lower abdominal pain. |
J. Douglas Bremner
See book keywords and concepts |
| If you have tried several medications and have severe depression, you might consider ECT or VNS as a last resort. |
Gary Null and Amy McDonald
See book keywords and concepts |
| Patient Story: Tobacco Allergy_
A high school teacher and principal developed a severe depression. In fact, I believe he was misdiagnosed as a schizophrenic. He exhibited what we call a straightforward, deep-seated, endogenous depression. He was in a mental hospital for about a year or two, and then discharged. He was so depressed that no one could live with him. His wife divorced him and eventually he was living with his aunt, who looked after him as if he were a child. As a last resort, he was referred to me. |
Amarjit S. Basra
See book keywords and concepts |
 The procentual reduction of the Hamilton Rating Scale for Depression (HAM-D) score values after six weeks' treatment of patients with moderately severe depression were the same for the Hypericum extract given in a dosage of 500 mg extract corresponding to 8-10 mg bioactive compounds
(hypericins, hyperforin, xanthones, flavonoids, procyanidins all together) per day, and imipramine given in a concentration of 150 mg per day (see Figure 1.7). This means that 8-10 mg Hypericum extract's bioactive constituents together are therapeutically equivalent to 150 mg imipramine. |
Eric R. Braverman
See book keywords and concepts |
 I've watched patients with severe depression and problems with rage completely turn their lives around. Every day my office successfully treats common conditions such as insomnia, anxiety, exhaustion, infections, headache, high blood pressure, obesity, and attention deficit disorder. I have seen an Alzheimer's patient who couldn't even speak both recognize and greet me after consistent treatment. I've had patients close to death from cancer who have been helped by this brain-based approach. |
Robert S. McCaleb, Evelyn Leigh, and Krista Morien
See book keywords and concepts |
 John's wort with those of the synthetic tricyclic antidepressant drug imipramine in people with severe depression showed that the two test substances were comparable in effectiveness for patients with severe depression (see Specific Studies). Because the patients were severely depressed, the investigators used dosages of St. John's wort and imipramine that were twice as high as those used in earlier trials.5 The results of this study are promising, but more research is needed before St. John's wort can be recommended for people with severe depression. |
Joseph E. Mario
See book keywords and concepts |
 Excess may cause severe depression.
•RED ROOT Leaf and Root(Ceanothusamericana)Rhamnacia family; also called New Jersey Tea, Wild Snow Ball, and Mountain Sweet. Astringent, expectorant, sedative, antispasmodic, hemostatic. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
See book keywords and concepts |
 For more severe depression, higher intakes may be used, under the supervision of a healthcare professional.
Are there any side effects or interactions?
St. John's wort has a low incidence of side effects compared to prescription antidepressants. An adverse events profile of St. John's wort found that, of 14 controlled clinical trials, seven reported no adverse reactions, two had no information, and five reported a total of seven mild reactions.11 Adverse effects reported included stomach upset, fatigue, itching, sleep disturbance, and skin rash. |
Dr. Timothy Scott
See book keywords and concepts |
 A developed a severe depression in reaction to his wife's infidelity. He saw a psychiatrist and was given medication, but after 2 years of treatment with antidepressants, mood stabilizers, neuroleptics and ECT, his response was far from robust.49
The doctor had to stop working. (Who could work when filled with the multiple mind drugs he was given and the ECT he underwent?) Two more years of "treatment" followed. |
Jacky Law
See book keywords and concepts |
 While the herb had managed to help only 24% of cases of moderate to severe depression, the placebo scored 32%. It later emerged that Zoloft was also part of the trial and had helped 25%.14
The clinical difference is not that impressive - and it is getting worse. 'Somewhere between 30% and 50% of patients in depression trials get better when given fake pills,' says Leila Abboud in the Wall Street Journal, 'and that number has increased and become more volatile over time, making it more difficult to prove that a drug works. |
Mike Adams
See book keywords and concepts |
 I talked to cancer patients, diabetics, osteoporosis sufferers, and people with severe depression. In every case, I found that rarely did any get better under the care of a doctor. Sure, people were able to mask the symptoms of their diseases by "managing" them with prescription drugs, but nobody fundamentally healed. No one overcame their diseases. The results of conventional medicine, I quickly learned, were dismal. Patients weren't getting healthy, they were only becoming dependant on drugs! |
Jack Challem
See book keywords and concepts |
 Mild to moderate depression can be treated with both natural and pharmaceutical methods, whereas severe depression is typically very resistant to any treatment. More common "everyday" mood disorders, such as "down" days, irritability, impatience, anger, and hostility, affect millions of people to varying degrees.
The Gene Connection
Some genetic polymorphisms do increase the risk of depression and mood disorders. However, the impact of these polymorphisms depends on diet and stressful events. |
| If you have had serious episodes of mental illness, such as severe depression or schizophrenia, you may benefit from still-higher dosages of individual B vitamins. Under these circumstances it might be best to consult with a nutritionally oriented physician or psychiatrist. For referrals go to www.orthomed.org or www.acam.org.
Please note that high dosages of vitamin B2 will turn your urine bright yellow, but this is not harmful.
In the next chapter, we will focus on antioxidant nutrients, which help protect DNA from damage and also turn some genes on and off. |
Kelly Harford, M.C., C.N.C.
See book keywords and concepts |
 Symptoms range from digestive disturbances such as gas and bloating to severe depression and anxiety, and every other conceivable symptom that may be associated with food allergies or sensitivities. Regardless of any health benefits you may have heard associated with soy, if you have an allergy or intolerance to soy and can't digest it properly (and most Westerners can't!) it won't do you any good and may, in fact, be causing you harm. |
James F. Balch, M.D. and Mark Stengler, N.D.
See book keywords and concepts |
 Mustard is for people who suffer from severe depression that comes and goes without warning.
Star of Bethlehem will help people who need help coping with a shock or a crisis, even if the event occurred years ago.
Other Recommendations
• If you have problems with alcohol, be aware that some everyday products contain small amounts that may throw your good intentions off track. Avoid mouthwash, and read the labels on cold and flu medicines.
• Many people who abuse stimulants are actually trying to jump-start an underactive thyroid. |
Joe Graedon, M.S. and Teresa Graedon, Ph.D.
See book keywords and concepts |
 Reserpine is notorious for causing severe depression. Treating it with an antidepressant like Lexapro is not logical.
A meta-analysis of atenolol in the journal Lancet (November 6, 2004) "cast doubts on atenolol as a suitable drug for hypertensive patients." It may cause fatigue, dizziness, or depression in some patients, but such blood pressure medication should never be stopped suddenly!
Your father should discuss his symptoms with his doctor who should be able to control your dad's blood pressure without severe side effects like depression or fatigue. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
See book keywords and concepts |
| However, while Saint John's wort extract appears to be as effective as or possibly even more effective than conventional antidepressant drugs in mild to moderate depression, it does not appear to be as effective as conventional drugs in severe depression.
No significant side effects have been reported in the numerous double-blind studies. In a large-scale safety study involving 3,250 patients conducted in Germany, undesired side effects were reported in 79 patients (2.43 percent). The most frequently noted side effects were gastrointestinal irritation (0.55 percent), allergic reactions (0. |
Joseph E. Mario
See book keywords and concepts |
| B-Complex, extraB6,B-12, and Folic acid (for severe depression, requires Vitamin C for absorption). Don't forget the rare mineral Indium, to improve absorption and use of other food and nutrients.
•COMPULSIVE BEHAVIOR SEE Obsessive-Compulsive Behavior. •CONCENTRATION SEE Brain
•CONSTIPATION Inability to move stools, with symptomsof lethargy, lowback pain, headache, and anorexia. |
Email this page to a friend
